Rat CTR&RAMP3 CRE-Luc CHO
CBP71662
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| I. Background | |
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大鼠CTR（降钙素受体）与RAMP3（受体活性修饰蛋白3） 共表达时形成AMY3型胰淀素受体（AMY3），这是胰淀素受体家族的重要成员之一。相比CTR与RAMP1形成的AMY1受体，AMY3（CTR/RAMP3）对胰淀素和降钙素基因相关肽（CGRP）同样具有高亲和力。 |
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| II. Description | |
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Rat CTR&RAMP3 CRE-Luc CHO 药靶模型很好的模拟了体内 Rat CTR&RAMP3 的信号转导过程。 |
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| III. Introduction | |
| Expressed gene: | Rat CTR&RAMP3 |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K + 10%FBS + 5μg/ml Puromycin + 5μg/ml Blasticidin + 600μg/ml Hygromycin B |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Functional assay for Rat CTR&RAMP3 |
| Transducer: | Gs |
IV. Representative Data Figure 1. Dose Response of Rat CTR&RAMP3 CRE-Luc CHO(C14).  Figure 2. HTRF cAMP Assay with Rat CTR&RAMP3 CRE-Luc CHO(C14） . |
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